Trabzonspor broke the deadlock with Danish forward Andreas Cornelius at the 24th minute at Antalya Stadium.
Antalyaspor leveled the match with a penalty goal from Alfredo Kulembe Ribeiro, known as Fredy, at the 34th minute.
At the 73rd minute, midfielder Dorukhan Tokoz scored an own goal to help Antalyaspor to taste a home victory.
The latest Turkish Super Lig defeat for Trabzonspor was on March 8 against Alanyaspor with a 3-1 score.
Despite the loss to Antalyaspor, Trabzonspor, who are nine points ahead of second-place Ittifak Holding Konyaspor remained at top of the Super Lig standings with 39 points.
Antalyaspor jumped to the 10th spot with 21 points.
Saturday's results:
VavaCars Fatih Karagumruk - Ittifak Holding Konyaspor: 1-4
Caykur Rizespor - Goztepe: 3-1
Medipol Basaksehir - Kasimpasa: 2-1
