Italy will face North Macedonia at home in a playoff semifinal next March, and the winner will play away at either Portugal or Turkey for a spot in the World Cup.
Also in the 12-team draw, Scotland will face Ukraine at home, and the winner will play at Wales or Austria in the final of their bracket.
Russia will host Poland for the right to face Sweden or the Czech Republic in their bracket final. Russia or Poland will host the final.
The six playoff semifinals will be played as single-leg elimination games March 24. The three finals are played five days later.
The three winners will complete Europe's entry of 13 nations in the 32-team lineup in Qatar.
FIFA will make the tournament draw on April 1 in Doha.
The playoffs feature the 10 teams who finished second in their qualifying groups along with two teams — Austria and the Czechs — who won Nations League groups last year.
