If Besiktas do not secure three points in the Sunday evening fixture at Galatasaray's Turk Telekom Arena, second-placed Fenerbahce could draw level on 73 points when they face Basaksehir on Monday night.
Galatasaray have little to play for, having dropped to sixth place, 28 points behind the leaders.
Following the derby, Besiktas face Osmalispor at home and Konyaspor away in the remaining fixtures.
The Istanbul derby is due to kick off at 8 p.m. local time (1700 GMT).
Fenerbahce will visit the Basaksehir Fatih Terim Stadium in Istanbul on Monday, hoping to keep pace with Besiktas. The match is due to start at 8 p.m. local time (1700 GMT).
Super Lig fixtures:
Saturday:
Medicana Sivasspor vs Genclerbirligi
Gaziantepspor vs Eskisehirspor
Osmanlispor vs Bursaspor
Sunday:
Akhisar Belediyespor vs Kayserispor
Trabzonspor vs Caykur Rizespor
Mersin Idmanyurdu vs Antalyaspor
Galatasaray vs Besiktas
Monday:
Torku Konyaspor vs Kasimpasa
Medipol Basaksehir vs Fenerbahce
If Besiktas do not secure three points in the Sunday evening fixture at Galatasaray's Turk Telekom Arena, second-placed Fenerbahce could draw level on 73 points when they face Basaksehir on Monday night.
Galatasaray have little to play for, having dropped to sixth place, 28 points behind the leaders.
Following the derby, Besiktas face Osmalispor at home and Konyaspor away in the remaining fixtures.
The Istanbul derby is due to kick off at 8 p.m. local time (1700 GMT).
Fenerbahce will visit the Basaksehir Fatih Terim Stadium in Istanbul on Monday, hoping to keep pace with Besiktas. The match is due to start at 8 p.m. local time (1700 GMT).
Super Lig fixtures:
Saturday:
Medicana Sivasspor vs Genclerbirligi
Gaziantepspor vs Eskisehirspor
Osmanlispor vs Bursaspor
Sunday:
Akhisar Belediyespor vs Kayserispor
Trabzonspor vs Caykur Rizespor
Mersin Idmanyurdu vs Antalyaspor
Galatasaray vs Besiktas
Monday:
Torku Konyaspor vs Kasimpasa
Medipol Basaksehir vs Fenerbahce
